Can you help to wrte an essay on these two biotec questions? - what to wrte in 1st birthday book
particularly in relation to specific diseases, such as gene therapy to discuss may be used one day to routinelytreat diseases?
d like to discuss transgene expression in bacteria can be enhanced to a product that can be commercially available produce rapidlyisolated with vectors?
1 comment:
First muscular dystrophy Duchenne muscular dystrophy. In this disease, the dystrophin gene on the X chromosome is not functional, and the protein dystrophin, which does not occur in the body (only men (in general) because they have only 1 X chromosome, your copy will not work if use a backup copy). Without it, muscle regeneration is impossible, and the muscles deteriorate, which is very weak muscles. Once the patient sits in a wheelchair and died in adulthood (usually) due to an error or failure of the heart muscle of the diaphragm. The idea of gene therapy for this disease is (a sample of tissue from the mother, or sometimes a father or brother received) and to grow the cells in the laboratory. The healthy cells are injected into the muscles in the hope that it will not help the situation, to regenerate some of the muscles (as they are normal cells with the normal operation of the dystrophin gene - The mother of DMD, because them two X-chromosomes) and finally (hopefully the place of non-functional gene) with a functional gene by healthy cells to reproduceSeveral cells healthy and will soon surpass the cells with the functional gene. Peter Law (I think that's his name), this method has been researching and now has a factory in Singapore, where this treatment is for something like $ 15,000 per child.
I really do not know the second question, because not really know what you mean by maximizing the expression of the transgene. I think it means he has to achieve something with plasmids with a specific gene is not for every product you try. examply for human insulin is often placed in a bacterial plasmid and in cells, and the gap, and repeat to grow is injected, which ends sense copies of insulin produced in the plasmid population, and the more insulin. Insulin, then harvested from bacteria and used for insulin injections for diabetics. I think I am better. sorry.
Good luck!
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